Chronic Migraine
Conditions
Brief summary
Infiltration of the greater occipital nerve (GON) with local anaesthetics and corticosteroids is a treatment option for cluster headache. Corticosteroids may be helpful in reducing the pain intensity and frequency in chronic migrtaine. This RCT is set up to assess efficacy and safety of sub-occipital steroid injections with local anesthetic in patients with chronic migraine.
Detailed description
Infiltration of the greater occipital nerve (GON) with local anaesthetics and corticosteroids is a treatment option for cluster headache. In general, there is a marked paucity of evidence concerning GON blocks in migraine. Corticosteroids may be helpful in reducing the pain intensity and frequency in these patients. This is an RCT to assess efficacy and safety of sub-occipital steroid injections with local anesthetic in patients with chronic migraine.
Interventions
Infiltration of the greater occipital nerve .
Sponsors
Jakob Møller Hansen, MD.
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Chronic migraine
Exclusion criteria
* Medication overuse headache
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of migraine days | 8 weeks | Number of days fulfilling the ICHD criteria for migraine |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of days with severe headache days | 8 weeks | Number of days with severe headache days |
| Medication use | 8 weeks | use of medication recorded during the 8 weeks |
| Responder rate | 8 weeks | number of patients with more than 50% reduction in migraine |
| Number of migraine attacks | 8 weeks | Number of attacks fulfilling the ICHD criteria for migraine |
Countries
Denmark
Contacts
Primary ContactJakob Møller Hansen
Outcome results
None listed