Flaccid Muscle Tone
Conditions
Brief summary
Mapping Human Muscle Satellite Cell Fate By Real-Time Imaging
Detailed description
The aim of this study is to obtain human muscle samples for cell culturing to analyze muscle cell development in real-time to uncover factors that influence growth.
Interventions
PROCEDUREmuscle biopsy
a muscle sample will be taken from the mid-thigh (Vastus Lateralis) and analyzed
Sponsors
Purdue University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
20 Years to 29 Years
Healthy volunteers
Yes
Inclusion criteria
-Inclusion Criteria: * men 20-29 yrs * BMI between 20 and 34.9 * Fasting Glucose \<110 mg/dL * Blood Pressure \<160/100mm Hg * Non-Diabetic * LDL-Cholesterol \<160mg/dL * Triacylglycerol \<400 mg/dL * Makers of kidney, liver, and heart functions within 10% of clinical normalcy * \<1.5hr /wk of habitual aerobic exercise training and no resistance exercise training in the past 6 months
Exclusion criteria
* men \<20or\>29 yrs * BMI between \<20 and \>34.9 * Fasting Glucose \>110 mg/dL * Blood Pressure \>160/100mm Hg * Non-Diabetic * LDL-Cholesterol \>160mg/dL * Triacylglycerol \>400 mg/dL * Pre-existing kidney or liver conditions --\>1.5hr /wk of habitual aerobic exercise training and no resistance exercise training in the past 6 months * Currently taking prescribed blood thinners
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mapping Human Muscle Satellite Cell Fate By Real-Time Imaging | <10 hrs | this study is to obtain human muscle samples for cell culturing which will be exposed to a novel real-time imaging technique in order to elucidate factors that influence muscle satellite cell growth. |
Countries
United States
Outcome results
None listed