Prognostic Factors , Morbidity and Mortality in Patients With Neuromuscular Disorders Admitted in ICU

Prognostic Factors, Morbidity, Mortality and Long Term Survival in Patients With Neuromuscular Disorders Admitted in Intensive Care Unit

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02685215

Enrollment

800

Registered

2016-02-18

Start date

2016-03-31

Completion date

2019-12-31

Last updated

2019-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intensive Care (ICU) Myopathy, Muscular Dystrophies

Keywords

intensive care unit, muscular dystrophy, mortality, prognosis, tracheostomy

Brief summary

Muscular dystrophies are neuromuscular disorders with disability. Restrictive pulmonary failure and cardiomyopathy affect prognosis.The investigators aim to establish predictive factors for mortality and morbidity in Intensive care unit (ICU ) and to describe the long term follow up after ICU discharge.

Detailed description

Muscular dystrophies are neuromuscular disorders with disability. Restrictive pulmonary failure and cardiomyopathy affect prognosis. Little is known about morbidity and mortality of patients with muscular dystrophies admitted in intensive care unit (ICU).The investigators aim to describe the spectrum of patients with muscular dystrophies admitted in ICU , to establish predictive factors for ICU mortality and morbidity and to describe the long term follow up after ICU discharge.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* admitted in ICU * Duchenne muscular dystrophy * Becker muscular dystrophy * LGMD * Steinert disease * Pompe disease * FSHD * metabolic disease * mitochondrial disease * congenital myopathy * others neuro-muscular diseases

Exclusion criteria

* brain injury * minor patient

Design outcomes

Primary

Measure	Time frame
ICU mortality	1 month

Secondary

Measure	Time frame
tracheostomy in ICU	1 month
predictive factors for re admission in ICU	1 year
long term survival after ICU stay	5 years
decline of vital capacity after ICU stay	2 years

Countries

France

Outcome results