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Sore Throat Prevention Following Intubation

Comparison Between Xylocaine Gel as Endotracheal Cuff Lubricant Versus Dexamethasone 8 mg Intravenously or Both for Sore Throat Prevention Following Intubation: Interventional Study

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02682134
Enrollment
300
Registered
2016-02-15
Start date
2015-11-30
Completion date
2016-02-29
Last updated
2016-02-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sore Throat

Keywords

Sore Throat, Intubation, Xylocaine, Dexamethasone

Brief summary

The aim of this interventional study is to find out the incidence of sore throat among intubated patients in Jordan university hospital and to find out which is preventive and effective method to decrease sore throat;is it xylocaine gel on endotracheal cuff as lubricant versus dexamethasone 8 mg intravenously or both.

Detailed description

Three groups were divided into: first group received xylocaine gel as endotracheal cuff lubricant,second group received dexamethasone 8 mg intravenously and third group received both( xylocaine and dexamethasone). The investigator compared between the three groups regarding sore throat in intubated patients and followed them up to 48 hours.

Interventions

First group were given xylocaine

DRUGDexamethasone

Second group were given Dexamethasone

DRUGXylocaine and Dexamethasone

Third group were given both Xylocaine and Dexamethasone

Sponsors

University of Jordan
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
15 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* ASA 1-3. * Elective VS Emergency. * Cuffed endo-tracheal tubes. * Different types of surgery.

Exclusion criteria

* Pregnant ladies. * ICU patients. * \<15 years of age * Laryngeal mask airway

Design outcomes

Primary

MeasureTime frameDescription
Comparison in preventing sore throat: xylocaine gel versus dexamethasone or both following intubation.4 monthsQuestionnaire follow up in intubated patients.

Secondary

MeasureTime frameDescription
Sore throat SCALE4 monthsSore throat scale from None,mild,moderate till severe.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026