Acute Kidney Injury, Delirium, Stroke
Conditions
Brief summary
Through a series of sequential analyses, retrospective database exploration looking for linkages and associations between the use of processed electroencephalogram (EEG) and/or cerebral saturation monitoring and patient outcomes post-cardiothoracic surgery will be explored.
Detailed description
The purpose of this study is to mine the Premier Healthcare Database to: 1. define the incidence of post-operative cognitive complications, acute kidney injury and stroke after specific cardiac surgical procedures (defined as: coronary artery bypass graft \[CABG\], Aortic Valve Replacement, Mitral valve repair, Mitral valve replacement, thoracic aortic operation, combined CABG and Valve replacement or repair ; and 2. Determine the incremental increase in the length of hospitalization and cost of hospitalization among cardiac surgical patients who suffer postoperative cognitive complications, acute kidney injury and stroke; and 3. Determine the effectiveness of intraoperative neuromonitoring with cerebral saturation and/or processed electroencephalogram (EEG) monitoring on the incidence of post-operative cognitive complications, acute kidney injury and stroke as a consequence of specific cardiac surgery procedures. The Premier Healthcare Database is a privately owned database that represents approximately 1/5th of all United States hospitalizations annually. It includes all International Classification of Diseases-9th Revision (ICD-9) and International Classification of Diseases-Clinical Modification (ICD-9-CM) diagnosis and procedure codes recorded by the hospital, as well as a limited set of Current Procedural Terminology (CPT)-4 codes. Within the database, discharge-level data include information on patient and provider characteristics, diagnoses and procedures, hospital resource utilization, and charges/cost data for all entries, including pharmacy charges.
Interventions
None listed
Sponsors
Medtronic - MITG
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
Yes
Inclusion criteria
* All adult (age \>=18 years) hospitalized patients who underwent major cardiac surgical procedure requiring cardiopulmonary bypass captured in the premier database from January 1, 2010 - December 31, 2014 (5 year period)
Exclusion criteria
* \<18 years of age * Cardiac procedures not requiring cardiopulmonary bypass
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Delirium: Incidence of post-operative cognitive complications identified by ICD-9 diagnosis code | 5 years | Incidence of post-operative cognitive complications identified by International Classification of Disease (ICD-9) diagnosis code |
| Acute Kidney Injury: Incidence of acute kidney injury identified by ICD-9 diagnosis code | 5 years | Incidence of acute kidney injury identified by ICD-9 diagnosis code |
| Stroke: Incidence of stroke identified by ICD-9 diagnosis code | 5 years | Incidence of stroke identified by ICD-9 diagnosis code |
Countries
United States
Outcome results
None listed