Acute Hyponatremia
Conditions
Keywords
Monopolar, Bipolar, TURP syndrome, hyponatremia
Brief summary
Aim of this prospective clinical study was to compare two different surgical techniques and used solutions on serum electrolytes, bleeding and Transurethral Resection of Prostate (TURP) syndrome undergoing TURP. Fifty-three patients scheduled for elective TURP were enrolled in this prospective clinical study. Patients were included one of two groups (Group Monopolar and Group Bipolar).
Detailed description
Background and Purpose: Aim of this prospective clinical study was to compare two different surgical techniques and used solutions on serum electrolytes, bleeding and Transurethral Resection of Prostate (TURP) syndrome undergoing TURP. Methods: Fifty-three patients scheduled for elective TURP were enrolled in this prospective clinical study. Patients were divided into two groups. Patients in Group M (Monopolar) (n=25) were used monopolar resectoscope (Karl Storz, Tottling, Germany) and 5% mannitol as irrigating solution. Patients in Group B (Bipolar) (n=25) were used bipolar resectoscope TURis (OLYMPUS, Tokyo, Japan) and isotonic saline as irrigating solution. Patients who received spinal anaesthesia were given 2.5-3 ml 0.5% hyperbaric bupivacain intrathecally and others were given general anaesthesia. Patients demographics, prostate volumes, hemodynamic parameters, volumes of irrigation and IV solutions were recorded. Blood samples were collected preoperatively (control), 45 minutes after the induction (2nd Measurement) and 1 hour after the end of the operation for analyzing serum electrolytes, osmolarity, hemoglobin values.
Interventions
OTHER5% Mannitol
Traditional monopolar TURP was performed by using and irrigation fluid containing 5% mannitol ( Resectisol Eczacibasi-Baxter).
OTHER0,9% Sodium chloride
Bipolar TURP was carried out by using a 24 Fr TURis (OLYMPUS) resectoscope and irrigation fluid containing 0,9 % sodium chloride.
DEVICEmonopolar resectoscope
DEVICEbipolar resectoscope TURis
Sponsors
Istanbul University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
MALE
Age
50 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Men were older than 50 years * Men suffered from symptomatic benign prostatic hyperplasia.
Exclusion criteria
* History of severe heart failure * History of respiratory failure * History of bleeding diathesis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Serum sodium level | 0-3 hours | Sodium level (meq /L) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Serum osmolarity | 0-3 hours | Osmolarity (mosm/kg) |
| Serum potassium levels | 0-3 hours | Potassium level (meq/L) |
| Serum hemoglobin level | 0-3 hours | Hemoglobin level (g /dL) |
Other
| Measure | Time frame | Description |
|---|---|---|
| Systolic blood pressure | 0-3 hours | mm Hg |
| Diastolic blood pressure | 0-3 hours | mm Hg |
| Heart rate | 0-3 hours | beat/min |
Countries
Turkey (Türkiye)
Outcome results
None listed