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Understanding the Effects of Intervention on the Brain in Autism

Understanding the Effects of Intervention on the Brain in Autism

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02680015
Enrollment
400
Registered
2016-02-11
Start date
2010-08-31
Completion date
2023-05-31
Last updated
2023-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asperger Disorder, Autism, Autism Spectrum Disorder, PDD-NOS

Keywords

PEERS, friendships, brain

Brief summary

This study examines how the PEERS (Laugeson & Frankel, 2010; Laugeson, 2016) social-behavioral intervention affects social relationships and brain development and function in autistic preschoolers, adolescents, and young adults.

Interventions

BEHAVIORALPEERS

Social-behavioral intervention designed to help individuals with Autism Spectrum Disorder make and keep friends.

Sponsors

Marquette University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender
ALL
Age
4 Years to 28 Years
Healthy volunteers
Yes

Inclusion criteria

* Verbal, speaking in full sentences * Meets ASD criteria * Meets IQ criteria \>70

Exclusion criteria

* schizophrenia or bipolar disorder

Design outcomes

Primary

MeasureTime frameDescription
Social Responsiveness Scale (SRS: Constantino, 2005)within two weeks of PEERS completionQuestionnaire completed by caregivers on social function and autism symptoms. Will be aggregated by group; no individual reports will be used.
Test of Adolescent Social SKills (TASSK: Laugeson & Frankel, 2010)within two weeks of PEERS completionQuestionnaire completed by participants with Autism Spectrum Disorder. Measures knowledge of the PEERS intervention concepts. Will be aggregated by group; no individual reports will be used.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026