Stomach Neoplasms
Conditions
Keywords
early gastric cancer, lifestyle
Brief summary
The purpose of this study is to determine whether positive lifestyle interventions (diet modification and smoking cessation) are effective in the prevention of gastric pre-cancer and cancer occurrences and reccurence of gastric cancer after endoscopic resection.
Interventions
BEHAVIORALActive measures of lifestyle modification
Sponsors
Shandong University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Intervention model description
Participants are assigned to lifestyle intervention group or the control group without lifestyle intervention.
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* diagnosis of chronic atrophy gastritis proved by gastroscopy biopsy pathology or early gastric cancer patients who have recieved endoscopic resection * have one or several bad lifestyle habits such as eating too much salt, eating too few fruits, smoking, drinking wine, and lack of sleep.
Exclusion criteria
* patients who refuse to change lifestyle according to the trial plan
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| gastric caner occurrence | 4 years | gastric cancer proved by gastroscopy biopsy |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| All cause mortality | 5 years | — |
| gastric tissue DNA methylation change of selected genes | 4 years | All patients have gastric biopsy through gastroscopy at the enrollment time and the last follow-up. DNA methylation status of selected genes are tested. |
Countries
China
Outcome results
None listed