Tumor of the Orbit
Conditions
Brief summary
Orbital masses develop at the expense of the orbital structures lacrimal glands, oculomotor muscles, optic nerve, meningeal spaces, peripheral nerves, bone wall, orbital fat, lymphoid structures or vascular structures. These masses can be tumors, benign or malignant, or pseudotumor, mainly represented by specific or non-specific orbital inflammation. Pathology is of considerable importance for the diagnosis and the treatment of those masses. However, biopsy or surgical resection of the orbital masses is sometimes difficult and dangerous outside expert centers. The identification of a non-invasive technique for distinguishing tumors from pseudotumors, thus avoid in some cases a biopsy, would be a major contribution for the patients. Quantitative analysis of the ultrasound exam with doppler of those masses could identify diagnostic criteria, especially for the lacrimal gland, easily explorable.
Interventions
Ultrasound exam of the orbit
Sponsors
Fondation Ophtalmologique Adolphe de Rothschild
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patient aged 18 years or more * with an orbital mass for which a biopsy and/or a surgical removal is planned * before surgery or biopsy
Exclusion criteria
* pregnancy * breast feeding * patient under a legal protection procedure * patient denying to participate to the study * lack of affiliation to a social security system
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity, expressed as a percentage, of the ultrasound exam with Doppler, the pathological exam being the gold standard | One month |
| Specificity, expressed as a percentage, of the ultrasound exam with Doppler, the pathological exam being the gold standard | One month |
Countries
France
Outcome results
None listed