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The Lamina Cribrosa (LC) Changes in the Eyes After Laser-Assisted in Situ Keratomileusis (LASIK)

The Lamina Cribrosa (LC) Morphologic Changes in the Eyes After Laser-Assisted in Situ Keratomileusis (LASIK)

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02676557
Enrollment
40
Registered
2016-02-08
Start date
2014-04-30
Completion date
2015-03-31
Last updated
2016-02-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The Lamina Cribrosa and Optic Nerve Head Changes

Brief summary

The burden of LASIK surgery on optic nerve head (ONH) has been controversial. Until now, the change of retinal nerve fiber layer (RNFL) thickness was used as the indicator of the study. In the present study, the investigators intended to investigate whether the changes of the deep and superficial structures around ONH exist or not using EDI OCT.

Interventions

DEVICEExposed to the high pressure during the surgery

Sponsors

Samsung Medical Center
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* the myopic patients who were supposed to undergo LASIK surgery in the Samsung Medical Center

Exclusion criteria

* Optic nerve head abnormalities at preoperative examination * Previous ocular surgical history

Design outcomes

Primary

MeasureTime frameDescription
Change of lamina cribrosa (LC) depthbefore the surgery, postoperative 1 day, 1 week, 1 month, and 3 monthsmicro millimeter
Change of lamina cribrosa (LC) thicknessbefore the surgery, postoperative 1 day, 1 week, 1 month, and 3 monthsmicro millimeter
Change of optic nerve head (ONH) widthbefore the surgery, postoperative 1 day, 1 week, 1 month, and 3 monthsmicro millimeter

Secondary

MeasureTime frameDescription
Change of optic nerve head minimum rim widthbefore the surgery, postoperative 1 day, 1 week, 1 month, and 3 monthsmicro millimeter

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026