CORPUS BIOPSIES, Gastric Antrum, Helicobacter Pylori
Conditions
Brief summary
There are controversies about the best sites -biopsy based -tests for H pylori associated gastritis. The study is designed to evaluate the optimal site of gastric mucosal biopsy for identification of Helicobacter pylori, especially in case of gastric atrophy and/or intestinal metaplasia.
Detailed description
. The study is designed to evaluate the optimal site of gastric mucosal biopsy for identification of Helicobacter pylori, especially in case of gastric atrophy and/or intestinal metaplasia. 400 patients with dyspepsia are planned to be enrolled in this study. in addition to the routine antral biospy, corpus biospies are taken to evaluate the optimal site of gastric mucosal biopsy for identification of Helicobacter pylori, especially in case of gastric atrophy and/or intestinal metaplasia.
Interventions
OTHERENDOSCOPIC GASTRIC BIOPSIES FROM ANTRUM AND BODY
ENDOSCOPIC GASTRIC BIOPSIES FROM ANTRUM AND BODY
Sponsors
Mansoura University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* Patients included in this study are those with peptic ulcer disease, previous upper gastrointestinal surgery, a known or a suspected past history of H.pylori eradication therapy, a personal or first-degree family history of gastric cancer
Exclusion criteria
* those having received antibiotic or proton pump inhibitor treatment one month beforehand
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| H PYLORI POSITIVITY | 2 YEARS |
Countries
Egypt
Outcome results
None listed