Maternal-Fetal Relations
Conditions
Keywords
Cardiac Surgery, Maternal sound, Cortisol, Blood sugar, Stress
Brief summary
A newborn's recognition and preference for their mother's voice occurs early in life, very likely during fetal development. Maternal voice stimuli undergo a unique form of cerebral processing that lends support for the existence of neurophysiologic mechanisms that reflect a child's preference for his/her mother's voice. This study aims to evaluate and compare the effect t of maternal sound listening in children undergoing cardiac surgery on stress response and physiological parameters.
Detailed description
Children (4 to 8 years) undergoing repair of Atrial Septal Defect (ASD). Patients will be randomized into two equal groups (30 in each group) (control group and maternal sound group); in control group patients listened to a blank CD, while in maternal sound group patients listened to a recorded CD where the mother singing the most popular songs their children like or telling a story to their children. Baseline stress markers (blood glucose and plasma cortisol) sampled the morning before scheduled operation. A interview with the patients and their parents before operation to collect the questionnaire regarding patient's characteristic (age, sex, weight and height), patient's clinical data (medical diagnosis and American Society of Anesthesiologists physical status) and haemodynamic data (blood pressure, heart rate, oxygen saturation on room air, temperature). In addition, the researcher interviewed with the mothers to record on one CD their voice while they are singing the most popular songs their children like or telling a story to their children to help them to sleep to be used during intra-operative period in maternal sound group.
Interventions
BEHAVIORALControl group
Patients in the control group listened to a blank CD connected to the patient ears before induction of anesthesia and continued during intra operative period till extubation in intensive care unit
BEHAVIORALMaternal sound group
The recorded maternal voice (while they are singing the most popular songs their children like or telling a story to help their children to sleep) listened by CD player connected to the patient ears before induction of anesthesia and continued during intra operative period till extubation in intensive care unit
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
4 Years to 8 Years
Healthy volunteers
No
Inclusion criteria
* Age range 4-8 years * Elective cardiac surgery * Atrial Septal Defect (ASD) repair with Cardiopulmonary bypass
Exclusion criteria
* Previous cardiac surgery * Diabetes mellitus * Hearing impairment * Psychiatric illness * Neurological illness.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Blood cortisol level | Up to 24 hours | Blood sample will be taken at preoperative, at sternotomy, after 10 minutes of cross clamping during cardiopulmonary bypass, during rewarming and at extubation |
| Blood sugar level | Up to 24 hours | Blood sample will be taken at preoperative, at sternotomy, after 10 minutes of cross clamping during cardiopulmonary bypass, during rewarming and at extubation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain assessment | Within the first 24 hours | Pain assessment after extubation by Objective Pain Scale (OPS) |
| Sedation assessment | Within the first 24 hours | Sedation assessment after extubation by Richmond Agitation Sedation Scale (RASS) |
| Post Traumatic Stress Disorder | Within the first postoperative week | An interview conducted with the patients and their parents by researcher blinded to the group randomization within the first postoperative week |
| Post hospital behavior questionnaire | Within the first postoperative week | An interview conducted with the patients and their parents by researcher blinded to the group randomization within the first postoperative week |
Countries
Egypt
Outcome results
None listed