Glaucoma
Conditions
Brief summary
Measurement of corneal temperature gives indirect information about the ocular blood flow. For this reason corneal temperature can be used as a surrogate to quantify ocular blood flow. It can be measured by means of infrared thermography. This test, however, is not used in an everyday clinical routine so far. In this study is investigated if ocular blood flow disturbances in glaucoma patients can be diagnosed by means of infrared thermography. Corneal temperature are measured in normal tension glaucoma patients and healthy controls before and after cold provocation test. In the group of patients and the group of controls, subjects with and without a primary vascular dysregulation (PVD) are included. This will allow to analyze and compare the influence of cold provocation on corneal temperature (and indirectly ocular blood flow) in these study Groups.
Interventions
DEVICEinfrared thermography
measurement of corneal temperature by infrared thermography before and after cold provocation
Sponsors
University Hospital, Basel, Switzerland
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
for Patients: * Glaucoma * Age 18-65
Exclusion criteria
for patients: * No Glaucoma * Alcohol consumption * Smoking Inclusion Criteria for Control: * No Glaucoma * Age 18-65
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Corneal temperature measurement by infrared thermography | 2 measurements with interval of 5 minutes starting at baseline | measurement of change in corneal temperature starting with first measurement at Baseline and second measurement after 5 minutes |
Countries
Switzerland
Outcome results
None listed