Genetics, Gynecologic Surgical Procedures, Quality of Life, Uterine Myomectomy
Conditions
Brief summary
This project focuses on myomectomy patients in reproductive age. The aim is to study both the molecular characteristics of uterine fibroids and to characterize the clinical effects of surgical treatment. Patient series is mainly retrospective and consists of individuals who have undergone myomectomy at Helsinki University Central Hospital (HUCH) during 2009-2015. In addition, the investigators have started a prospective sample collection starting in October 2015, collecting samples from myomectomies. Clinical data sources include medical records, specific questionnaires and a quality of life -questionnaire filled by patients.
Interventions
PROCEDUREMyomectomy
The patient series consists of consecutive patients scheduled for elective laparotomic, traditional laparoscopic or robotic assisted laparoscopic myomectomy. The surgical method is selected based on clinician´s preference.
Sponsors
University of Helsinki
Helsinki University Central Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Uterine leiomyoma * Seeking for surgery
Exclusion criteria
* Language proficiency in Finnish, Swedish or English
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Quality of life measured by a validated questionnaire (UFS-QOL) | Two years | UFS-QOL: Uterine Fibroid Symptom and Health-Related Quality of Life Questionnaire |
Secondary
| Measure | Time frame |
|---|---|
| Pregnancy rate after myomectomy, data collected with questionnaire | Five years |
Countries
Finland
Contacts
Primary ContactPäivi I Pakarinen, MD PhD
Backup ContactAnna K Äyräväinen, MD
Outcome results
None listed