Alzheimer's Disease
Conditions
Brief summary
Alzheimer Disease (AD), characterized by cognitive and psycho-behavioral troubles, concerns essentially 65 years old and older patients. Antalgic and psychotropic treatments have adverse effects in old people, and have to be used carefully. To improve the pain support and limit the drug consumption, it is possible to perform therapies without drugs. Among them, musical intervention represents an interesting complementary support, to deal with physical and moral pain in AD.
Detailed description
Alzheimer Disease (AD), characterized by cognitive and psycho-behavioral troubles, concerns essentially 65 years old and older patients. At this age, comorbidities are frequent and numerous, and often linked to pain. The prevalence is comprised between 40 and 85% according to different studies. Antalgic and psychotropic treatments have adverse effects in old people, and have to be used carefully. To improve the pain support and limit the drug consumption, it is possible to perform therapies without drugs. Among them, musical intervention represents an interesting complementary support, to deal with physical and moral pain in AD. The primary outcome is to evaluate the singing support on physical pain, by comparison with a control activity : painting session.
Interventions
BEHAVIORALSinging sessions.
Patients will be in singing work groups, and will participate to these sessions during 12 weeks, with one session per week of 2 hours.
BEHAVIORALPainting sessions.
Patients will be in painting groups, they will participate to this work session during 12 weeks, with one session of 2 hours per week.
Sponsors
Centre Hospitalier Universitaire de Saint Etienne
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients 60 years old and older, fulfilling the diagnostic criteria for Alzheimer's disease to a mild dementia stage, or mild cognitive impairment * Delay of at least one month between the diagnosis and the early work sessions * If use of psychotropic drugs, they must be stabilized for 3 month * If analgesics consumption level 2 or 3 they must be stabilized for 1 month * With a score greater than or equal to 22 on the simplified visual scale (EVS) pain. * Visual capabilities , auditory and oral or written expression in French language sufficient for conducting clinical and neuropsychological evaluations; * MMSE \> 20 * Patient affiliated or entitled to a social security scheme
Exclusion criteria
* Patient with a different etiology of cognitive disorder that of Alzheimer's disease * Patients with severe disease, progressive or unstable nature which may interfere with the evaluation variables * Patient with blindness or deafness could compromise its assessment * Patient under guardianship
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Score at the EVS = simplified visual scale | Month 1 | To evaluate the efficacy of the singing sessions on pain in Alzheimer's Disease patients (beginning stage), by comparison with a control activity (painting), on pain intensity. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Score at the EN (digital scale) scale | Month 1 | To evaluate the efficacy of the singing sessions on pain in Alzheimer's Disease patients (beginning stage), by comparison with a control activity (painting), on pain intensity. |
| Score at the BPI (Brief Pain Inventory) scale : Brief pain Inventory | Month 1 | To evaluate the efficacy of the singing sessions on pain in Alzheimer's Disease patients (beginning stage), by comparison with a control activity (painting), on pain intensity. |
Countries
France
Outcome results
None listed