Anxiety, Depression
Conditions
Brief summary
The purpose of this study is to test causal links between dimensions of positive and harsh parenting and children's brain responses to rewards and errors, using a parenting intervention.
Detailed description
Depression and anxiety are among the most frequently diagnosed psychological disorders, with persistent patterns of impairment evident from childhood through adulthood. Impaired functioning of core brain systems that respond to reward and errors may increase risk for depression and anxiety. Importantly, these neural risk markers for depression and anxiety appear to be shaped, at least in part, by environmental input. Problematic parenting is a key environmental factor involved in the intergenerational transmission of depression and anxiety. Low positive parenting is associated with blunted brain responses to reward and harsh parenting is associated with heightened brain responses to errors. This study uses an evidence-based parenting program to test causal links between dimensions of positive and harsh parenting and children's brain responses to rewards and errors. Participants will include 80 6- to 7-year-old children and their mothers who will be randomly assigned to participate in a parenting program (Parent Child Interaction Therapy: PCIT) or to a waitlist control group, and brain responses to rewards and errors will be assessed pre- and post-intervention.
Interventions
PCIT includes 12-16 sessions across two phases: the first focused on enhancing positive parenting during child-directed interactions, and the second focused on reducing harsh parenting during parent-directed interactions. Parents receive feedback and coaching on their interactions with the child during sessions.
Sponsors
Study design
Eligibility
Inclusion criteria
* Child is 6-7 years old * Maternal history of anxiety or depression * Maternal self-report of low positive/high harsh parenting
Exclusion criteria
* Child has developmental disorder
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Event-Related Potentials (ERP) | On average, 1 month after intervention | ERP responses to reward (i.e., feedback negativity) and errors (i.e., error-related negativity) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Parenting quality | On average, 1 month after intervention | Observational assessments of positive and harsh parenting |
| Child anxiety symptoms | On average, 1 month after intervention | Parent Questionnaire |
| Child depressive symptoms | On average, 1 month after intervention | Parent Questionnaire |
| Child anxiety | On average, 1 month after intervention | Structured diagnostic interview |
| Child depression | On average, 1 month after intervention | Structured diagnostic interview |
Countries
United States