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Shaping Neural Activity Through Parenting

Targeting Biomarkers of Risk for Depression and Anxiety Through a Parenting Intervention

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02667522
Acronym
SNAP
Enrollment
160
Registered
2016-01-29
Start date
2016-04-30
Completion date
2019-01-31
Last updated
2018-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety, Depression

Brief summary

The purpose of this study is to test causal links between dimensions of positive and harsh parenting and children's brain responses to rewards and errors, using a parenting intervention.

Detailed description

Depression and anxiety are among the most frequently diagnosed psychological disorders, with persistent patterns of impairment evident from childhood through adulthood. Impaired functioning of core brain systems that respond to reward and errors may increase risk for depression and anxiety. Importantly, these neural risk markers for depression and anxiety appear to be shaped, at least in part, by environmental input. Problematic parenting is a key environmental factor involved in the intergenerational transmission of depression and anxiety. Low positive parenting is associated with blunted brain responses to reward and harsh parenting is associated with heightened brain responses to errors. This study uses an evidence-based parenting program to test causal links between dimensions of positive and harsh parenting and children's brain responses to rewards and errors. Participants will include 80 6- to 7-year-old children and their mothers who will be randomly assigned to participate in a parenting program (Parent Child Interaction Therapy: PCIT) or to a waitlist control group, and brain responses to rewards and errors will be assessed pre- and post-intervention.

Interventions

BEHAVIORALParent Child Interaction Therapy (PCIT)

PCIT includes 12-16 sessions across two phases: the first focused on enhancing positive parenting during child-directed interactions, and the second focused on reducing harsh parenting during parent-directed interactions. Parents receive feedback and coaching on their interactions with the child during sessions.

Sponsors

Stony Brook University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Investigator)

Eligibility

Sex/Gender
ALL
Age
6 Years to 7 Years
Healthy volunteers
Yes

Inclusion criteria

* Child is 6-7 years old * Maternal history of anxiety or depression * Maternal self-report of low positive/high harsh parenting

Exclusion criteria

* Child has developmental disorder

Design outcomes

Primary

MeasureTime frameDescription
Event-Related Potentials (ERP)On average, 1 month after interventionERP responses to reward (i.e., feedback negativity) and errors (i.e., error-related negativity)

Secondary

MeasureTime frameDescription
Parenting qualityOn average, 1 month after interventionObservational assessments of positive and harsh parenting
Child anxiety symptomsOn average, 1 month after interventionParent Questionnaire
Child depressive symptomsOn average, 1 month after interventionParent Questionnaire
Child anxietyOn average, 1 month after interventionStructured diagnostic interview
Child depressionOn average, 1 month after interventionStructured diagnostic interview

Countries

United States

Contacts

Primary ContactKristin Bernard
kristin.bernard@stonybrook.edu6316327576

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026