Paediatric Malignancies
Conditions
Brief summary
The constitution of a biological samples bank, attached to epidemiological studies Cohort F-CCSS on iatrogenic effects of treatment of childhood cancer, will identify genetic variants that can modulate the iatrogenic risks of these treatments. The main objective is to provide a biological samples bank to consider, besides the carcinogenic risks, the risk of other iatrogenic diseases in these children, in particular cardiac, cerebrovascular, lung, bone and kidney. These conditions can be very incapacitating and in some cases, fatal. Their impact, however, is poorly estimated as occurring in adulthood, they are rarely made in relation to the treatment received in childhood. The overall project is expected to eventually better define the iatrogenic effects prevention strategies for cancer treatment.
Interventions
PROCEDUREsaliva samples
PROCEDUREblood samples
Sponsors
Gustave Roussy, Cancer Campus, Grand Paris
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients treated for a first cancer in childhood * Adult patients * Signed informed consent * Patient insured or enjoying a social security scheme
Exclusion criteria
* Minor patients * Under legal protection measure patients * Refusal of consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Study of genetic factors who might lead to secondary iatrogenic pathology due to treatment of a childhood cancer | seven years |
Countries
France
Contacts
Primary ContactCarole Rubino, MD
Backup ContactNadia Haddy, MD
Outcome results
None listed