Appetite, Faba Bean, Insulin, Post-prandial Blood Glucose, Satiety Hormones
Conditions
Brief summary
To describe the effect and mechanisms of action faba bean powder and fractions (protein, starch and fiber) on glucose and insulin homeostasis, food intake, satiety and metabolic regulation in young adults (18 to 30 years).
Detailed description
The overall objective is to describe the effect and mechanisms of action of faba bean powder and fractions (protein, starch and fiber) on glucose and insulin homeostasis, food intake, satiety and metabolic regulation in young adults (18 to 30 years). The specific objectives are to test the acute effects of different faba bean ingredient smoothie on: 1) post-prandial blood glucose, appetite, satiety hormone and insulin for 200 minutes, and 2) food intake 120 minutes following consumption of the faba bean smoothie. Two short-term acute studies will be conducted to meet these objectives. Both acute studies will follow a randomized, double blinded, balanced, repeated measures design and the same protocol; except one will have an ad libitum pizza meal (study 1), while the other will have a fixed pizza meal (study 2) at 120 minutes. Half the participants will have blood drawn by IV and the other half will be finger prick.
Interventions
OTHERFaba bean powder smoothie
Breakfast smoothie with 32 g whole faba bean powder (300g).
OTHERFaba bean protein concentrate smoothie
Breakfast smoothie with 32 g faba bean protein concentrate.
OTHERFaba bean starch smoothie
Breakfast smoothie with 33 g faba bean starch.
OTHERFaba bean protein isolate smoothie
Breakfast smoothie with 32 g faba bean protein isolate.
OTHERNon-pulse smoothie smoothie
Control smoothie with 32 g corn maltodextrin without added faba bean fractions.
Sponsors
University of Manitoba
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
MALE
Age
20 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy * non-smoking males * aged 20-30 years (min/max age) * a body mass index between 20 and 25 kg/m2 (the range generally accepted as ideal/healthy by Health and Welfare Canada)
Exclusion criteria
* individuals diagnosed with diabetes * those on medication * breakfast skippers * on an energy restricted diet * this study excludes females because appetite and blood glucose during the female menstruation cycle changes due to fluctuations in hormones
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| blood glucose | 0-200 minutes | measured by finger prick blood samples by glucose meters |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| satiety hormones | 0- 200mins | measured by enzyme-linked immunosorbent assay (ELISA) |
| insulin | 0-200mins | measured by ELISA |
| appetite | 0-200 minutes | measured by VAS questionnaire |
| physical comfort | 0-200 minutes | measured by VAS questionnaire |
| energy/fatigue | 0-200 minutes | measured by VAS questionaire |
| food intake | 120 minutes following consumption of the faba bean smoothie | energy intake at ad-libitum pizza meal |
Countries
Canada
Outcome results
None listed