Effect of Epidural Dexamethasone on Labor Analgesia

Epidural Levobupivacaine Versus A Combination of Levobupivacaine and Dexamethasone in Parturients Receiving Epidural for Vaginal Delivery Analgesia: A Comparative, Dose Ranging and Safety Evaluation Study

Status

UNKNOWN

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02665936

Enrollment

Registered

2016-01-28

Start date

2015-10-31

Completion date

2016-02-29

Last updated

2016-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labor

Keywords

epidural analgesia

Brief summary

The purpose of this study is to detect whether the addition of epidural dexamethasone will prolong labor analgesia.

Interventions

DRUGLevobupivacaine

Levobupivacaine will be given epidurally and the duration of analgesia will be calculated

DRUGDexamethasone and levobupivacaine

dexamethasone 4 mg epidurally with levobupivacaine and duration of analgesia is measured

DRUGLevobupivacaine and Dexamethasone

dexamethasone 8 mg epidurally with levobupivacaine and duration of analgesia is measured

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 40 Years

Healthy volunteers

Inclusion criteria

* ASA physical status I, II * normal vaginal delivery In early active phase of labor * singleton cephalic presentation at term

Exclusion criteria

* complicated pregnancies * morbid obesity * diagnosed fetal abnormalities * contra-indications to regional anesthesia

Design outcomes

Primary

Measure	Time frame
Duration of epidural analgesia	an average of 5 months

Secondary

Measure	Time frame	Description
Time of onset of sensory block at level T10	an average of 5 months	From the onset of active stage till the end of labor

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026