Assesment of Salivary Alpha-amylase Levels Before and After Ovulation

Assesment of Salivary Alpha-amylase Levels Before and After Ovulation: A Randomized Controlled Trial

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02664480

Enrollment

100

Registered

2016-01-27

Start date

2016-01-31

Completion date

2016-03-31

Last updated

2016-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Salivary Amylase

Keywords

Salivary Alpha-amylase, ovulation

Brief summary

Investigators aimed to investigate whether there is an association between ovulation and salivatory alpha amylase (sAA) activity in menstrual cycles during a month period in a group of reproductive women.

Detailed description

Saliva is a readily available specimen, which can be collected by noninvasive procedures and contains many hormones, drugs and antibodies of interest in screening and diagnosis. With a salivary specimen, one can collect multiple specimens at the optimum times for diagnostic information. Saliva can be collected in remote sites by unskilled personnel and, is stable at ambient temperatures for several weeks. Because of diurnal and monthly variations, several steroid hormones need multiple samples collected early in the morning or late at night or at the same time every day for a month to give meaningful results. Such collections are often very expensive, inconvenient or impossible to do with blood. Investigators aimed to investigate whether there is an association between ovulation and salivatory alpha amylase (sAA) activity in menstrual cycles during a month period in a group of reproductive women.

Interventions

OTHERSalivary alpha-Amylases

Investigators will collect Salivary alpha-Amylases before and after ovulation

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* Clinical diagnosis of PCOS (study group) * Reproductive age regular menses women

Exclusion criteria

* pregnancy, * breastfeeding, * known liver disease, * alcohol abuse, * diabetes mellitus, * smoking * treatment with oral glucocorticoids * treatment with hormonal contraceptives.

Design outcomes

Primary

Measure	Time frame	Description
Changes of Salivary Alpha-amylase activity	3rd and 24th day of menstrual cyclus	Saliva samples will be taken 2 times during the menstrual cyclus (3th day and 24th day).

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026