Heart Failure
Conditions
Keywords
Heart Failure, Bioimpedance analysis, Fluid overload
Brief summary
The aim of this study is to investigate whether the objective measurement of fluid overload by bioimpedance analysis (Body Composition Monitor-BCM) in patient with acute decompensated heart failure would improve the diuretic therapy.
Interventions
In the experimental group, the diuretic therapy adjusted according to the result of the BCM analysis.
Sponsors
Peter Studinger
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients with known or newly discovered chronic heart failure admitted to hospital because of the clinical signs of acut cardiac decompensation
Exclusion criteria
* High level of fatigue (the patient cannot stand on a scale) * Amputated upper and/or lower limb(s) * The BCM analysis is not possible technically (e.g. open wounds on the limbs) * Severe obesity (\>130 kg) * Patients on chronic hemodialysis or peritoneal dialysis * Severe fluid volume in the transcellular space * Patients with a unipolar pacemaker whose sensitivity threshold is very low * Pregnancy, lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Re-hospitalization rate | 12 months |
Secondary
| Measure | Time frame |
|---|---|
| All cause mortality | 12 months |
Other
| Measure | Time frame | Description |
|---|---|---|
| Quality of life | 3 months | Measured by validated questionnaire |
| Renal function decline | 3 months | Measured by estimated glomerular filtration rate (ml/min/1.73m2) |
Countries
Hungary
Outcome results
None listed