Skip to content

The Quantitative Changes in Palatal Donor Sites Thickness After Free Gingival Graft Harvesting

The Quantitative Changes in Palatal Donor Sites Thickness After Free Gingival Graft Harvesting

Status
Completed
Phases
Early Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02659904
Enrollment
40
Registered
2016-01-21
Start date
2015-02-28
Completion date
2016-01-31
Last updated
2016-01-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival Recession, Healthy

Keywords

Free gingival graft, Palatal donor site healing

Brief summary

Our primary objective in this clinical intervention study, therefore, was to explored the effect of residual tissue thickness on the palatal mucosa healing from baseline to 1, 3 and 6 months after free gingival graft harvesting in order to determine as soon as possible to re-harvest gingival graft from same site.

Detailed description

Forty individuals (19 males and 21 females; age range: 18-35 years) were enrolled in the study. Based on the remaining tissue at donor site after free gingival graft harvesting, individuals were divided into two groups: 1.0-1.9 millimeter (mm) remaining tissue at donor site after harvesting (n = 20), 2-2.9 mm remaining tissue at donor site after harvesting. Tissue filling in defect area from three points (mesial, central and distal) was measured at various time-points (baseline, post-operative 1, 3, 6 months).

Interventions

OTHERLess than 2 mm remaining palatal tissue thickness

The greater palatine and incisive nerves were blocked with 2% lidocaine, 1:100,000 epinephrine injection. After preparation of the recipient bed, free gingival graft was harvested using a handle with knife at palatal donor side with acrylic stent guidance.

OTHER2 mm or more remaining palatal tissue thickness

The greater palatine and incisive nerves were blocked with 2% lidocaine, 1:100,000 epinephrine injection. After preparation of the recipient bed, free gingival graft was harvested using a handle with knife at palatal donor side with acrylic stent guidance.

Sponsors

İlker KESKINER
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
No

Inclusion criteria

* All individuals received oral hygiene instructions and full-mouth scaling was performed. -They were instructed to perform a non-traumatic brushing technique (Roll) using an ultra-soft toothbrush * Individuals were re-evaluated at 8 weeks after initial therapy, and only full mounth plaque score and full mounth bleeding score \<15% were enrolled to the surgical procedure * mucogingival defects which for soft tissue graft application were indicated * For Less than 2 mm group, between 2.5 and 3.4 mm palatal thickness at each measurement points before graft harvesting * For 2 mm or more group, between 3.5 and 4.4 mm palatal thickness at each measurement points before graft harvesting.

Exclusion criteria

* periapical or palatal pathologies, * absence teeth from canine to first molar, * excessive forces including mechanical forces from orthodontics and occlusion, * systemic diseases that would contraindicate for periodontal surgery or interfere with tissue healing, chronic high-dose steroid therapy, radiation or immunosuppressive therapy, pregnancy, lactation, smoking, or allergy or sensitivity to any drug * Study participants had no history of drug therapy known to interfere with healing and to cause gingival enlargement * Individuals who had complication such as bleeding, necrosis and delay healing during or after surgery were excluded from the study.

Design outcomes

Primary

MeasureTime frame
Change in remaining palatal tissue thicknessFrom baseline remaining palatal tissue thickness to post-operative 1, 3, 6 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026