Diabetes, Obesity
Conditions
Keywords
Food intake, Satiety, Appetite, Glycemia, Faba bean, Protein, Snack
Brief summary
The investigators hypothesized that consuming crackers or pasta enriched with faba bean fractions (faba bean protein concentrate, faba bean protein isolate, faba bean flour and faba bean starch), would reduce the blood glucose response to the meal compared to foods without faba bean components and reduce food intake at a meal
Interventions
DIETARY_SUPPLEMENTCrackers/pasta with added faba bean protein concentrate
Protein concentrate treatment
DIETARY_SUPPLEMENTCrackers/pasta with added faba bean protein isolate
Protein isolate treatment
DIETARY_SUPPLEMENTCrackers/pasta with added faba bean starch
Starch treatment
DIETARY_SUPPLEMENTCrackers/pasta with added faba bean flour
Flour treatment
DIETARY_SUPPLEMENTCrackers/pasta with no faba bean fraction
Control treatment
Sponsors
University of Toronto
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
MALE
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Non-smoking * No metabolic disease * BMI 20 - 25 kg/m\^2 * Male * Age 18-30
Exclusion criteria
* Intolerance to treatments * Currently taking appetite-modifying medications * Restrictive eating * Smoking * Over- or underweight * Breakfast-skipping
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in blood glucose levels | Starting at the beginning of each session (0 minutes, before consumption of treatment) and every 15 - 30 minutes up to 200 minutes (time of completion of each session) | Each participant will attend 5 sessions in total (randomized 5-arm cross-over design) |
| Change in gut hormone levels measured in the blood | Starting at the beginning of each session (0 minutes, before consumption of treatment) and every 30 minutes up to 200 minutes (time of completion of each session) | Each participant will attend 5 sessions in total (randomized 5-arm cross-over design) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Subjective appetite | From 0 to 200 minutes | Measured using Visual Analog Scales (VAS) |
| Ad libitum food (pizza meal) intake as measured by the amount of pizza (in grams) consumed during the 20 minute period | 120 minutes after completion of treatment, 20 minutes were allocated to allow for pizza consumption | Each participant will also answer questions related to physical comfort, motivation to eat, and rating feelings of energy and fatigue using Visual Analog Scales (VAS) |
Countries
Canada
Outcome results
None listed