Behavioral
Conditions
Keywords
cognition, anesthesia, surgery, stress, child
Brief summary
The role of surgical stress and anesthesia is unknown in the early childhood. In vitro and animal studies showed a risk for treatment with anesthesia in the developmental brain. Furthermore, stress is also an important risk factor for cognitive impairment. Therefore, the investigators want to investigate in a clinical prospective cohort study the role anesthesia and surgery on different cognitive parameters and self-controling mechanisms in children under 3 years.
Detailed description
In order to investigate the role of anesthesia and / or surgery on cognitive abilities the investigators want to perform a prospective cohort study in children under 3 years. Three groups should be compared: i) control without anesthesia / surgery, ii) children with only anesthesia, and iii) children with both surgery and anesthesia. All children will be investigate before and after intervention. Different behavioral scales will be used for detailed cognitive abilities and self-regulatory skills.
Interventions
BEHAVIORALanesthesia - surgery
Sponsors
Konstanze Plaschke
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
9 Months to 3 Years
Healthy volunteers
Yes
Inclusion criteria
* Age 9 month to 3 years with or without anesthesia / surgery
Exclusion criteria
* Psychiatrical, neurological, oncological diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Global cognitive abilities | 4-6 weeks | Bayley Scale |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| surgery-associated data | 1 - 3 days | reason of surgery |
Countries
Germany
Outcome results
None listed