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Measurement of Ocular Tensional Fluctuation by Triggerfish Lens Before and After Cataract Surgery in Patients With Exfoliative Glaucoma

Status
Terminated
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02658071
Acronym
TRIGGERFISH
Enrollment
6
Registered
2016-01-18
Start date
2016-03-15
Completion date
2017-12-29
Last updated
2026-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract, Exfoliative Glaucoma

Keywords

exfoliative glaucoma, cataract, ocular pressure

Brief summary

Glaucoma is a very frequent disease in Brittany. In glaucoma the retinal ganglion cells and their axons slowly die with visible changes at the optic nerve head (cupping). Without early diagnosis and effective treatment or with delayed treatment decrease of visual acuity or blindness become. In secondary pseudoexfoliation glaucoma grayish-white deposits of abnormal proteins are found on all surfaces of eye irrigated by the aqueous humor. The deposits of PEX material inside the trabecular meshwork decrease aqueous humour outflow and the intraocular pression raise. The exfoliation material is found on the surface of the lens capsule with frequent developement of nuclear cataract . After cataract surgery the intra ocular pressure (IOP) decrease. Some recent study have found decreasing ocular volume variation associated to IOP fluctuation in night after cataract surgery in normal pressure glaucoma patients. In our study we want see if it's the same thing in pseudoexfoliation glaucoma patients.

Interventions

None listed

Sponsors

University Hospital, Brest
Lead SponsorOTHER
Sensimed AG
CollaboratorINDUSTRY

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult * Exfoliative glaucoma * Patient who need cataract surgery * Patient agree with study

Exclusion criteria

* Monophtalm patient * Patient with bleb after glaucoma surgery * Terminal glaucoma * Herpes * One year control impossible

Design outcomes

Primary

MeasureTime frameDescription
Measurement of ocular tensional fluctuation by Triggerfish lens before and after cataract surgery in patients with exfoliative glaucoma.During 24H00 before and after cataract surgeryVariation of ocular volume

Countries

France

Contacts

PRINCIPAL_INVESTIGATORCatherine COCHARD, Dr

University Hospital of Brest

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 9, 2026