Child Development, Helicobacter Pylori Infection, Iron Deficiency Anemia
Conditions
Brief summary
The investigators believe that there is an association between H. pylori infection and nutritional status and between H. pylori infection and cognitive development. The current study will examine this association in Israeli children, aged 6-12 years.
Interventions
None listed
Sponsors
Hillel Yaffe Medical Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
6 Years to 12 Years
Healthy volunteers
Yes
Inclusion criteria
* Informed consent by parents/guardians and children
Exclusion criteria
* Growth retardation history * History of prior therapy for H. pylori irradiation * Hematological disorders * Developmental delays
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in means of differences in height | Two years | The means of the differences in height for age Z score between baseline and follow-up visits |
| Changes in means of differences in weight | Two years | The means of the differences in weight for age Z score between baseline and follow-up visits |
| Changes in means of differences in body mass index | Two years | The means of the differences in body mass index for age Z score between baseline and follow-up visits |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes in Iron Biomarkers | Two years | The means of the differences in iron biomarkers (hemoglobin, ferritin, iron) between baseline and follow-up visits |
Other
| Measure | Time frame | Description |
|---|---|---|
| Changes in Intelligence quotient (IQ) scores | Two years | Changes in full-Scale IQ scores and-sub-scores on WISC test between baseline and 24-months follow-up visit: will be defined as the means of the differences of these scores. |
Countries
Israel
Contacts
Primary ContactAmit Hochberg, MD
Outcome results
None listed