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Right Lateral Positioning and Its Effect on Induction of General Anesthesia for Children

Right Lateral Positioning and Its Effect on Induction of General Anesthesia for Children

Status
Completed
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02654184
Enrollment
100
Registered
2016-01-13
Start date
2016-01-31
Completion date
2016-07-31
Last updated
2016-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia

Keywords

Right lateral, Induction, Children, Anesthesia

Brief summary

The quality of induction with sevoflurane, along with its ability to generate optimal conditions for Laryngeal Mask Airway (LMA) insertion without supplemental opioids or muscle relaxants, has also been well documented. An ideal inhalation induction technique besides being rapid and comfortable for the patient should be economical. To achieve rapidity, use of vital capacity breaths with 8% sevoflurane is a more popular method of induction compared with the conventional incremental induction.

Detailed description

100 pediatric patients (age range, 1 to 8 years) scheduled for lower abdominal surgery under anesthesia will be included. All children in both groups will be premedicated with midazolam, 0.5 mg/kg orally, about 30 minutes before the induction of anesthesia. A parent or guardian accompanied the child into the operating room to allow the child to remain calm and cooperative for inhalation induction. Before induction, pulse oximetry and electrocardiogram monitoring will be attached. For each group, inhalation induction was initiated using a face mask using tidal volume and vital capacity breathing in high sevoflurane concentration (8%).

Interventions

PROCEDUREsupine position

Anesthesia induction with sevoflurane for the patient while he is in supine position.

Anesthesia induction with sevoflurane for the patient while he is in right lateral position.

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
1 Years to 8 Years
Healthy volunteers
No

Inclusion criteria

* Children aged 1 years to 8 years * Children with ASA class I/II and their willingness to participate in the study

Exclusion criteria

* Known seizure disorder * Craniofacial abnormalities/difficult airway * Cardiopulmonary or neuromuscular defects * Hepatic or renal insufficiency * Expected difficult intravenous (IV) cannulation (eg, dark complexion, obese) * Catching colds during the past four weeks

Design outcomes

Primary

MeasureTime frameDescription
Induction timean expected 30 minutesThe time from starting induction of anesthesia until successful insertion of the LMA (seconds)

Secondary

MeasureTime frameDescription
LMA trials (Number of patients in each group required insertion of an LMA more than once)an expected 60 minutesNumber of patients in each group required insertion of an LMA more than once
Blood pressureDuration of from starting induction of anesthesia till LMA an expected average of 60 minutesSystolic, diastolic and mean blood pressure mm Hg
Heart rateDuration of from starting induction of anesthesia till LMA an expected average of 60 minutesHeart rate beats per minute
Oxygen saturationDuration of from starting induction of anesthesia till LMA an expected average of 60 minutesOxygen saturation %

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026