Skip to content

Central and Peripheral Arterial Pressure Decoupling In Cardio-Pulmonary Bypass

Central and Peripheral Arterial Pressure Decoupling In Cardio-Pulmonary Bypass

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02652858
Acronym
CAPD-CPB
Enrollment
40
Registered
2016-01-12
Start date
2016-01-31
Completion date
2016-09-30
Last updated
2025-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Surgery, Cardiopulmonary Bypass, Extracorporeal Circulation

Brief summary

Central and peripheral arterial pressure decoupling occurs in some clinical conditions like sepsis or cardiopulmonary bypass. This decoupling may leed to unsuitable decisions such as the use of catecholamines. The aim of this study is to evaluate the pulse wave's speed as a marker of central and peripheral arterial pressure decoupling in a scheduled condition which is the cardiopulmonary bypass during cardiac surgery.

Interventions

PROCEDURENon-invasive blood pressure oscillometer (NIBP) implementation

Implementation of two additional NIBP on humeral and femoral sites.

Sponsors

Université Joseph Fournier Grenoble 1
CollaboratorUNKNOWN
Hospices Civils de Lyon
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Scheduled patient for coronary or valvular surgery with cardiopulmonary bypass * Cardiopulmonary bypass is at least 90 minutes * Written consent is needed

Exclusion criteria

* Patient with heart rate disorder * Patient with aortic dissection * Dobutamine/milrinone/levosimendan treatment before surgery * Patient with heart rate due to a pacemaker

Design outcomes

Primary

MeasureTime frameDescription
Measurement of femoral, radial and humeral pulses during a cardiopulmonary by-pass (CPBP).Day one (6 times)Pulse wave's speed is calculated using 1) time between ECG R-wave and local detection of the pulse wave (femoral, humeral and radial) 2) a length from heart to these sites. Wave detection at femoral and humeral sites will use oscillometry and wave detection at radial site will use an invasive catheter which is always set for this surgery.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026