Pulmonary Embolism
Conditions
Keywords
pulmonary embolism, pulmonary disease, Lung Doppler signals
Brief summary
The LDS may contain information of significant diagnostic and physiological value regarding the pulmonary parenchyma and vasculature, as well as the cardio- vascular system in general. In pilot clinical studies of patients with acute decompensated heart failure (ADHF) as well as patients with Pulmonary Hypertension, LDS signals patterns unique to these conditions were identified. We believe that these newly discovered ultrasound signals might provide a non-invasive radiation-free means to diagnose and monitor patients with Pulmonary Embolism. The purpose of this study is to assess the utility of noninvasive assessment of lung Doppler signals performed via transthoracic parametric Doppler. The objective of the study is to evaluate the lung Doppler signals (LDS) in patients diagnosed with acute PE, in order to determine the potential assessment value of this non-invasive method in this potentially life threatening condition.
Interventions
RADIATIONDiagnostic ultrasound radiation
Recording Doppler ultrasound signals from the right chest wall
Sponsors
Echosense Ltd.
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Confirmed diagnosis of acute PE on CTA
Exclusion criteria
* Pregnant women * Inability to consent * Patients with severe chest wall deformity * Previously diagnosed PE * Pneumonia * Pulmonary edema * Pneumothorax * Severe COPD (gold class III, IV) * Hemodynamically unstable patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Identify lack of Lung Doppler signals in specific lung sections that were diagnosed obstructed by CT | 30min | The obstructed sections will be compared with healthy lung sections |
Countries
Israel
Outcome results
None listed