Sedation in ERCP
Conditions
Keywords
ketamine, propofol, pethidine, ERCP, endoscopist
Brief summary
The investigators aim to investigate the differences between ketamine propofol and pethidine propofol during ERCP in respect to endoscopist satisfaction.
Detailed description
The investigators aim to investigate the differences between ketamine propofol and pethidine propofol during ERCP in respect to endoscopist satisfaction, amount of propofol consumption Any desaturation or apnea will be recorded when the oxygen saturation (SpO2) dropped to \<90% , time for recovery ,post-operative nausea and vomiting, hallucinations and Ramsey sedation scores of all patients will be recorded perioperatively. The Aldrete score was used to measure recovery from anesthesia at 5 and 10 min after the procedure.
Interventions
DRUGketamine- propofol
1 mg x kg(-1) ketamine + 1.2 mg x kg(-1) propofol.
DRUGpethidine- propofol
1.1 mg x kg(-1) pethidine + 1.2 mg x kg(-1) propofol for sedation induction
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* both gender * age between 18-70
Exclusion criteria
* pregnant patients. * morbid obesity. * chronic obstructive pulmonary disease. * complicated airway. * American society of anesthesia (ASA) physical classification IV-V. * history of allergy or contraindications to the drugs used in the study * emergency need for ERCP. * those whose informed consent could not be signed. * those with possible complex ERCP.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| endoscopist satisfaction using 5 step scale (5= optimal condition; 1= poor condition) | Immediately after procedure. |
Other
| Measure | Time frame |
|---|---|
| amount of propofol consumed during procedure | Immediately after procedure. |
Countries
Egypt
Outcome results
None listed