Renal Insufficiency, Chronic
Conditions
Brief summary
The purpose of this study is to determine whether a supervised resistance exercise training during hemodialysis is effective to increase physical activity in daily life in patients with end stage renal disease.
Detailed description
The patients will be randomized into two groups: intervention and control groups. Patients in the intervention group will receive a supervised resistance exercise training, during hemodialysis, three times/week for 12 weeks, and patients allocate to the control group will received a passive stretching program during the same timeframe.
Interventions
During the first week of training will be conducted two sets of 10 repetitions, and from the second week of training until the twelfth will be performed three sets of 10 repetitions. The work rate will set to the tolerance of each patient as established by his/her inability to maintain Borg ratings for dyspnea and effort (10-point category-ratio Borg scale) scores between 4 and 6.
Sponsors
Federal University of Juiz de Fora
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with end stage renal disease on hemodialysis for at least three months * Sedentary for at least six months
Exclusion criteria
* Presence of physical limitations that prevent the implementation of physical tests * Presence of severe comorbidity and unstable (unstable angina, decompensated heart failure, myocardial infarction history of the past six months, cardiac arrhythmias, uncontrolled hypertension with systolic blood pressure ≥ 200 mmHg and / or diastolic blood pressure ≥ 120 mmHg, diabetes decompensated, severe lung disease, acute systemic infection as well as neurological disorders, musculoskeletal and osteoarticular or other disabling conditions according to the clinical judgment) * Hospitalization in the three months prior to study entry
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Physical Activity in Daily Life | 12 weeks | The physical activity in daily life will be estimated as the mean number of steps using a triaxial accelerometer. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Functional capacity | 12 weeks | The functional capacity will be assessed by six-minute walking test. |
| Quality of life | 12 weeks | The quality of life will be assessed by the 36-Item Short Form Health Survey (SF36). |
| Muscle function | 12 weeks | The muscle function will be assessed by electromyography. |
| Muscle strength | 12 weeks | The measurement of maximal voluntary strength of handgrip will be assessed by hydraulic model of dynamometer. |
| Depression and anxiety | 12 weeks | Depression and anxiety will be assessed by the Hospital Anxiety and Depression Scale. |
Countries
Brazil
Contacts
Primary ContactFelipe M Valle
Backup ContactMaycon Reboredo, DSc
Outcome results
None listed