Non-motor Symptoms and Brain Dopamine Transporter Binding

Non-motor Symptoms and Brain Dopamine Transporter Binding: An Observational Study in Parkinsonism

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02650843

Acronym

NMDAT

Enrollment

455

Registered

2016-01-08

Start date

2015-01-31

Completion date

2026-12-31

Last updated

2025-04-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson Disease, Parkinsonism

Keywords

Parkinsonism, DAT Dopamine transporter, SPECT

Brief summary

This project aims to clarify the role non-motor symptoms in the development of Parkinson's disease (PD) and to improve diagnostics at very early stages of PD. The project involves multidimensional measures of disease biomarkers together with brain dopamine transporter (DAT) imaging with \[123I\]FP-CIT single photon emission computed tomography (SPECT).

Interventions

OTHERDAT SPECT imaging

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 100 Years

Healthy volunteers

Inclusion criteria

* Male or Female * Age 18-100 years * Referred for clinical DAT SPECT in Turku or Helsinki

Design outcomes

Primary

Measure	Time frame
DAT SPECT striatal specific binding ratio	Up to 10 years

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 18, 2026