Dementia, Mild Cognitive Impairment, Stroke
Conditions
Keywords
Follow up studies, Risk factors
Brief summary
A prospective observational multicenter study aiming to describe incidence, and identify predictors for development of poststroke dementia (PSD) and mild cognitive impairment (MCI) after stroke
Detailed description
About 15000 Norwegians suffer a stroke every year and 2/3 will be more or less disabled. In addition to motor impairments and comorbidities, disability after stroke is often related to post stroke dementia (PSD) or mild neurocognitive disorder (NCD). However, these problems are hardly addressed in stroke or dementia research and frequently ignored in clinical practise. In the Nor-COAST study an interdisciplinary research group will collaborate to establish a research platform across all Norwegian Health Authorities. The overall aim of the study is to improve competence on PSD and NCD in order to improve individual health outcomes following a stroke. The specific objectives are to determine the incidence of PSD and NCD and the consequences on function and use of health care services and to enhance the early detection of PSD and NCD by identifying a set of risk factors, ranging from genetics to physical activity. The incidence and impact of PSD and NCD on function and use of health care services, medication and life-style changes are important when planning future health care services. Tools identifying patients at risk might improve diagnostic work up and together with knowledge on pathogenic aspects it will contribute to future treatment and prevention of PSD and NCD.
Interventions
None listed
Sponsors
Ullevaal University Hospital
Vestre Viken Hospital Trust
Haukeland University Hospital
University Hospital of North Norway
Norwegian University of Science and Technology
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Stroke diagnosis according to the WHO criteria
Exclusion criteria
* Not scandinavian speaking
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Score on the Montreal cognitive assessment (MOCA) | 18 months | Performance based test |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Score on the Montreal cognitive assessment (MOCA) | 3 months | Performance based test |
| Time spent in upright position | 3 months | measured by bodyworn sensors |
| Brain Imaging | 18 months | MRI |
| Score on Short Physical Performance Battery (sppb) | 3 months | Performance based test for mobility and lower extremity function |
| Selfreported habits concerning smoking, alcohol, diet and medication using standardised questionnaires | 3 months | — |
Countries
Norway
Outcome results
None listed