Embryo Transfer
Conditions
Brief summary
The embryo transfer implies transportation from the incubator where they have been at 37 ° C, to the transfer catheter inside a laminar flow hood whose working surface is also maintained at 37 ° C. . From the laboratory to the operating room the embryo is exposed to a temperature drop, and consequently thermal stress occurs, which may compromise its future viability. The aim of this study is to assess the possible improvement in the clinical results when the embryos are transported in a stable device to avoid the drop in temperature throughout the transfer process. With the use of this thermosetting device heated to 37 ° C, researchers expect a 15% increase in pregnancy rates.
Interventions
DEVICEThermostable device
Investigators place the catheter with the loaded embryos into a plastic device at 37ºC in order to maintain the temperature
Sponsors
Rafael Bernabeu Pérez
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Cryo-transfer cycles: transfer of embryos vitrified in previous cycles receiving donated eggs inseminated with either conjugal or donated sperm from Instituto Bernabeu bank.
Exclusion criteria
* Fresh cycles: transfer of fresh embryos (coming from donated or own eggs), and cryo-transfer cycles from vitrified embryos coming from own oocytes.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Ongoing Pregnancy rate | Ongoing pregnancy until 28th week of gestation | Achieving an ongoing pregnancy after embryo transfer |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Miscarriage rate | Loss of pregnancy up to 12 weeks of gestation | To know the embryonic loss rate after implantation |
| Implantation rate | Embryo implantation after 6-7 weeks of gestation | To know the embryo implantation rate after the embryo transfer |
Countries
Spain
Contacts
Primary ContactJorge Ten Morro, Ph.D.
Backup ContactJorge Ten Morro, Ph.D
Outcome results
None listed