Effects of Prehabilitation in Gastric Cancer Patients With Metabolic Syndrome on Perioperative Outcome

Effects of Pre-operative Prehabilitation on the Clinical Outcomes of Gastric Cancer Patients With Metabolic Syndrome Who Undergo Laparoscopic Radical Gastrectomies: A Polit Randomized Clinical Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02649348

Enrollment

Registered

2016-01-07

Start date

2015-09-30

Completion date

2018-02-28

Last updated

2018-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic Syndrome X, Stomach Neoplasms

Keywords

gastric neoplasm, metabolic syndrome, prehabilitation, pre-operative exercise, laparoscopic radical gastrectomy

Brief summary

A prospective randomised controlled trial to investigate the effects of a pre-operative prehabilitation protocol on clinical outcomes of gastric cancer patients with metabolic syndrome who undergo laparoscopic radical gastrectomies and to determine the underlying mechanisms.

Detailed description

To investigate the effects of a pre-operative prehabilitation protocol on clinical outcomes of gastric cancer patients with metabolic syndrome who undergo laparoscopic radical gastrectomies and to determine the underlying mechanisms.

Interventions

BEHAVIORALpre-operative prehabilitation

To climb six flights of stairs (approximately 20 meters in height) at least 6 times as a daily routine and adaptive simulated training of restrictive ventilation dysfunction (increased thoracic and decreased abdominal breathing compliance) following abdominal surgery by using a full elastic breathable abdominal bandage.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* histologically-proven pre-operative stage I-III gastric cancer * Combined with metabolic syndrome * Age limits from 18 to 80 years old * Classified into American Society of Anesthesiology (ASA) II or III surgical risk * no history of abdominal surgery on organs located at the abdominal supramesocolic level

Exclusion criteria

* Combined with severe cardiac or pulmonary disease or other organ dysfunction * ASA IV * The history of abdominal surgery * Conversion to open surgery * The presence of gastrointestinal obstruction, perforation or necrosis; * Declined to participate in this study

Design outcomes

Primary

Measure	Time frame
The proportion of postoperative complications	up to six months

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026