Thyroid Papillary Carcinoma
Conditions
Keywords
thyroid carcinoma, center lymph node dissection
Brief summary
This study recruit the patients with unilateral papillary thyroid cancer before operation,the patients agree to enter the test,and divided into experimental and control group.experimental group patients receive the surgery including unilateral thyroid lobectomy and bilateral central lymph node dissection.and control group receive the surgery including unilateral thyroid lobectomy and unilateral central lymph node dissection.last the investigators compare numbers of patient with tumor recurrence and metastasis rate of 5 years,numbers of metastatic lymph node,and numbers of participants with adverse events related to treatment between two groups in order to evaluate the significance of bilateral lymph node dissection.
Interventions
PROCEDUREsurgery：BCND（bilateral central lymph node dissection）
PROCEDUREsurgery：UCND（unilateral central lymph node dissection）
Sponsors
Fujian Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
15 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
according by thyroid carcinoma TNM(tumor,lymph node, metastasis) staging of NCCN (National Comprehensive Cancer Network) Inclusion Criteria: * 1.Unilateral thyroid papillary carcinoma 2.TNM staging: T1\ 2N0M0
Exclusion criteria
* 1.Bilateral thyroid papillary carcinoma 2.isthmus thyroid carcinoma 3.TNM staging: T3orT4 4.Clinic N1orM1
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| tumor recurrence | 5 years | numbers of patients with tumor recurrence |
| numbers of metastatic lymph node | 1 years | numbers of metastatic lymph node |
| adverse events related to treatment | 1 years | numbers of participants with adverse events including recurrent nerve injury，parathyroid injury，hemorrhage |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| relations between the lymph metastasis and TNM staging | 1 years | Coefficient R (SPSS software for correlation analysis) |
| relations between the lymph metastasis and tumor location | 1 years | Coefficient R (SPSS software for correlation analysis) |
Countries
China
Contacts
Primary Contactwenxin zhao, doctor
Backup Contactshouyi yan, master
Outcome results
None listed