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Caffeine Intake and Additive Effects on Cognition

Can Caffeine Intake Combined With Aerobic Exercise Leads to Cognitive Improvement and Psychomotor Performance in Trained Individuals?

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02647567
Acronym
Caffeine
Enrollment
20
Registered
2016-01-06
Start date
2015-05-31
Completion date
2015-12-31
Last updated
2016-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Cognitive, Aerobic Exercise, Performance

Brief summary

Caffeine is a methylxanthine commonly consumed by the population for their psychostimulant properties, and their intake when in moderate doses seem to produce positive effects on stress, mood and memory. So, understanding that a positive effect of aerobic exercise can be displayed also on cognition, as caffeine, when in proper proportions, the investigators do not know if the joining of the two strategies into a single activity would be able to promote additional effects enhancing cognitive processes related to memory, attention, and motor reaction time.

Detailed description

Determine if 500 mg of caffeine can generate additional effects to 30 minutes of aerobic exercise enhancing cognitive memory tasks (Rey Auditory Verbal Learning Test - RAVLT), attention (sustained attention span; working speed; Percentual of errors by confusion) and simple reaction time (SRT).

Interventions

The experimental group ingest 500 mg of caffeine before (60 min) aerobic exercise (procedure double blind), and perform a battery of neuropsychological and psychomotor tests. 1 min and 30 min after the exercise the subjects perform a new battery of neuropsychological and psychomotor tests.

The control group ingest 500 mg of placebo before (60 min) aerobic exercise (procedure double blind), and perform a battery of neuropsychological and psychomotor tests. 1 min and 30 min after the exercise the subjects perform a new battery of neuropsychological and psychomotor tests.

Sponsors

Universidade Federal do Rio de Janeiro
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
MALE
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* Fighting men * Low levels of consumption of caffeine daily

Exclusion criteria

* Use more than 400 mg caffeine day * Mental diseases * Cognitive deficits

Design outcomes

Primary

MeasureTime frame
Simple Reaction TimeAcute Change from Baseline Psychomotor test to 1 min after aerobic exercise, and after 30 min
Rey Auditory Verbal Learning TestAcute Change from Baseline Cognitive test to 1 min after aerobic exercise, and after 30 min
Sustained Attention TestAcute Change from Baseline Cognitive test to 1 min after aerobic exercise, and after 30 min

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026