Effect of a Bolus of 10 µg/kg of Alfentanil on the Pupillary Pain Index

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02646592

Enrollment

Registered

2016-01-05

Start date

2016-04-30

Completion date

2016-12-31

Last updated

2017-05-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia, Pain

Brief summary

This study aims to assess the Pupillary Pain Index before and after a bolus of alfentanil in children under general anesthesia, before skin incision.

Interventions

DRUGAlfentanil

Bolus of alfentanil 10 µg/kg 5 minutes before skin incision

DRUGsevoflurane or propofol

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

2 Years to 18 Years

Healthy volunteers

Inclusion criteria

* Elective surgery under general anesthesia * Written informed consent

Exclusion criteria

* Chronic pain * Preoperative analgesic drug * Neurologic disease * Ophtalmic disease

Design outcomes

Primary

Measure	Time frame	Description
Change between Pupillary Pain Index before and after alfentanil bolus	Five minutes before incision and just before incision. Each measure = 20 seconds	pupillometry

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 3, 2026