Clinical Use of Magnetic Resonance Perfusion Imaging to Qualitatively Assess Adequate Distal Perfusion After Endovascular Revascularization in Critical Limb Ischemia

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02646150

Acronym

MR CLI

Enrollment

Registered

2016-01-05

Start date

2015-12-12

Completion date

2021-11-01

Last updated

2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemia, Lower Limb, Perfusion

Keywords

Magnetic Resonance perfusion imaging, distal perfusion, Critical Limb Ischemia, endovascular revascularization

Brief summary

This study evaluates the clinical effectiveness of Magnetic Resonance(MR) perfusion imaging to qualitatively assess adequate distal perfusion after endovascular revascularization in Critical Limb Ischemia

Interventions

PROCEDUREMagnetic Resonance Perfusion Imaging

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age 20 and above * Critical limb ischemia with ulcer * Ankle brachial index(ABI) ≤ 0.9 or Toe brachial index (TBI) ≤ 0.5 or Transcutaneous oxygen pressure (TcPo2) ≤ 40mmHg * ≥ 70 percentage of stenosis of infrapopliteal artery on lower extremity computed tomography angiography or lower extremity doppler * Subject understands protocol and provides written, informed consent

Exclusion criteria

* Post-traumatic critical limb ischemia * Neurogenic limb ischemia * Life expectancy ≤ 2 years

Design outcomes

Primary

Measure	Time frame
The change of deoxyhemoglobin in MR imaging	6 months

Secondary

Measure	Time frame
The event rate of unplanned major and minor amputation in limb	6 months
The event rate of complete healing of lower extremity ulcer	6 months

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026