Transversus Abdominis Plane Block for Postoperative Analgesia in Living Donor Hepatectomy

Ultrasound-guided Transversus Abdominis Plane Block for Postoperative Analgesia in Living Donor Hepatectomy: Randomized Controlled Double-blinded Trial

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02645903

Enrollment

Registered

2016-01-05

Start date

2015-05-31

Completion date

2015-10-31

Last updated

2016-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Pain

Keywords

transversus abdominis plane block, living liver transplantation, postoperative analgesia

Brief summary

Living donor organ transplantation has increased in recent years due to an increased need for organs. The objective of this study was to investigate the effects of a TAP block on postoperative analgesia and opioid consumption in liver transplantation donors in whom a right lateral extending upper mid-line abdominal incision was used.

Detailed description

This prospective randomized controlled double-blinded study was conducted with 50 liver transplantation donors between 18-65 years who were scheduled to undergo right hepatectomy surgery. Cases to whom TAP block with ultrasound was applied after standard general anesthesia were determined as Group 1 and cases to whom only standard general anesthesia was applied, were determined as Group 2.

Interventions

DRUGTransversus Abdominis Plane Block

Cases to whom used bupivacaine with ultrasound guided transversus abdominis plane block was applied after standard general anesthesia were determined as Group 1

DRUGstandard general anesthesia

Cases to whom applied alone standard general anesthesia were determined as Group 2

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Liver transplantation donors

Exclusion criteria

* Patients with a history of allergy to the drugs used in the study protocol, coagulation pathology, opioid tolerance

Design outcomes

Primary

Measure	Time frame	Description
pain scores (at movement and at rest)	postoperatively at 24 hours	Pain scores were assessed using a visual analog scale (0: No pain, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10: Excruciating pain).

Secondary

Measure	Time frame	Description
morphine consumption	postoperatively at 24 hours	morphine consumption were measured in postoperatively 24 hours

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026