Chronic Periodontitis, Diabetes Mellitus, Type 2
Conditions
Keywords
Dental Scaling, Blood Glucose, Hemoglobin A, Glycosylated
Brief summary
The purpose of this study is to determine whether periodontal treatment improves the periodontal clinical parameters in the periodontal patients with diabetes regarding non-diabetics: two years follow-up.
Detailed description
All the subjects in the study will receive non surgical periodontal treatment in one session (full-mouth scaling and root planing). Clinical parameters will be assessed in all teeth (except third molars) by one experienced and trained examiner before treatment and every 3 months for 2 years. Visible plaque index (VPI) will be represented a mean percentage of sites with visible plaque calculated for all teeth analyzed (four sites per tooth). Others parameters will be assessed at six sites per tooth using a manual periodontal probe (15mm). Bleeding on probing (BOP) will be represented the mean percentage of sites with bleeding (up to 15 seconds after probing) calculated for all teeth analyzed. Probing depth (PD - distance between the gingival margin and the bottom of the sulcus/pocket), gingival recession (GR - distance between the cementoenamel junction and gingival margin) and clinical attachment level (CAL - distance between the cementoenamel junction and the bottom of the sulcus/pocket) will be represented a mean distance calculated per site for all teeth analyzed. For blood parameters, an outside laboratory will perform all blood analysis. It will be requested for each subject with diabetes (DG) at baseline, each 3 months post-treatment. Fasting plasma glucose (FPG) will be expressed in milligrams per deciliter and HbA1c will be expressed as a percentage. Statistical analysis will be performed using an available software program and the patient will be considered as the unit of analysis.The data will be processed and analyzed by descriptive and inferential statistics, probably nonparametric.
Interventions
PROCEDUREFull Mouth Scaling and Root Planing
This procedure was performed as described by Quirynen et al. 2005 with some modifications
Sponsors
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Eduardo Aleixo Figueira
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Clinical diagnosis of chronical periodontitis according to Lopez et al. 2002 (one or more teeth with at least one site with PD \>= 4mm or CAL \>= 3mm); * And have at least 8 natural teeth (excluding third molars), and older than 18 years and of both genders.
Exclusion criteria
* Any systemic diseases or complications (except Type 2 Diabetes Mellitus) such as cardiovascular disease, Alzheimer's, lung or brain diseases and metabolic syndrome; * Use of antibiotics or periodontal treatment within the past 6 months; * Long-term administration of anti-inflammatory or/and immunosuppressive agents; * Current smoker or former smoker for the past 5 years; * Pregnant or breastfeeding; * And presence of orthodontic appliances.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percentage of bleeding on probing | Baseline | The mean percentage of periodontal sites with bleeding on probing |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Probing depth (mm) | Baseline and at three, six, nine, twelve, eighteen and twenty four months | The mean of probing depth in millimeters calculated for periodontal sites. |
| Percentage of visible plaque index | Baseline and at three, six, nine, twelve, eighteen and twenty four months | The mean percentage of periodontal sites with visible plaque |
| Clinical attachment level (mm) | Baseline and at three, six, nine, twelve, eighteen and twenty four months | The mean of clinical attachment level in millimeters calculated for periodontal sites. |
Countries
Brazil
Contacts
Primary ContactBruno CV Gurgel, Doctor
Backup ContactEduardo A Figueira, Doctor
Outcome results
None listed