Hypercapnia During Shoulder Arthroscopy

The Effect of Hypercapnia on Regional Cerebral Oxygen Saturation in the Sitting Position

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02643030

Enrollment

Registered

2015-12-30

Start date

2012-03-31

Completion date

2015-10-31

Last updated

2015-12-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral Ischemia

Brief summary

The purpose of this study is to evaluate the effects of hypercapnia on hemodynamics and cerebral oxygenation during shoulder arthroscopy.

Detailed description

The patients are randomly allocated to receive normocapnia or hypercapnia . After the 70º sitting position, record the mean arterial pressure (MAP), heart rate, and regional oxygen saturation (rSO2).

Interventions

BEHAVIORALhypercapnia

Tidal volume (6 ml/kg) and respiratory rate is adjusted to achieve the objective values of ETCO2 45mmHg

BEHAVIORALnormocapnia

Tidal volume (10 ml/kg) and respiratory rate is adjusted to achieve the objective values of ETCO2 35mmHg

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

20 Years to 65 Years

Healthy volunteers

Inclusion criteria

* patients undergoing elective shoulder arthroscopic surgery

Exclusion criteria

* a history of age \> 65 years, morbidly obesity (BMI \> 30 kg/m2), diffuse lung disease, uncontrolled systemic hypertension, intracranial disease, cardiovascular and cerebrovascular disease.

Design outcomes

Primary

Measure	Time frame
Regional cerebral oxygen saturation	Change from Regional cerebral oxygen saturation at 2,4,6,8,10,20 min after anesthetic induction and sitting position

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026