Gabapentin in Treatment of Muscle Cramps in Patients With Liver Cirrhosis

Status

UNKNOWN

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02642484

Enrollment

200

Registered

2015-12-30

Start date

2018-12-31

Completion date

2022-12-31

Last updated

2018-01-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Cirrhosis

Brief summary

* Muscle cramps markedly affect the quality of life in cirrhotic patients with no highly effective drug. * Quinine was suggested for treatment of patients with muscle cramps in patients with liver cirrhosis. However, thrombocytopenia, cardiac arrhythmias and cinchonism are serious side effects.

Detailed description

• The aim of the study was to assess the efficacy and safety of Gabapentin in the treatment of muscle cramps in patients with liver cirrhosis.

Interventions

DRUGGabapentin

Gapapentin twice daily

DRUGCalcium Carbonate

calcium carbonate twice daily

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* liver cirrhosis patients

Exclusion criteria

* allergy to gapabentin. * pregnancy and lactation. Renal failure.

Design outcomes

Primary

Measure	Time frame
Number of muscle cramps	3 months

Countries

Egypt

Contacts

Primary ContactSherief M. Abd-Elsalam, Consultant

sherif_tropical@yahoo.com00201095159522

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026