Polypectomy
Conditions
Brief summary
Interval colon cancers are an important clinical issue. A recent paper from Pohl et al focused on non-pedunculated polyps of 5-20 mm, evaluating non complete polypectomy revealing that 10% of these polyps were not completely resected. This fact was attributed to size and histology. In this study the investigators want to evaluate the radical resection of non-pedunculated polyps of 5-20 mm by performing biopsies on the margins immediately after polypectomy, to establish if the use of Narrow Band Imaging (NBI) could be useful in the definition of the margins of the lesion before polypectomy.
Detailed description
Interval colon cancers are an important clinical issue. Literature dealing with technics and quality of polypectomy is scarce. A recent paper from Pohl et al focused on non-pedunculated polyps of 5-20 mm, evaluating non complete polypectomy and factors related to it, revealing that 10% of these polyps were not completely resected. This fact was attributed to size and histology (the majority of non completely resected ones, were polyps of 10-20 mm and with serrated characteristics at the histology). In this study the investigators want to evaluate the radical resection of non-pedunculated polyps of 5-20 mm by performing biopsies on the margins immediately after polypectomy, to establish if the use of Narrow Band Imaging (NBI) could be useful in the definition of the margins of the lesion before polypectomy.
Interventions
NBI to perform the polipectomy
no NBI to perform the polypectomy
Sponsors
Study design
Eligibility
Inclusion criteria
* Every polyp ≥ 5 mm and ≤ 20 mm
Exclusion criteria
* Inflammatory bowel Disease and/or International Normalized Ratio \> 1.5
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NBI efficacy in predicting radicality of polypectomy by taking random biopsies of margins after resection of the lesion | 12 months |
Countries
Italy