ARDS
Conditions
Keywords
echocardiography
Brief summary
Assessment of right ventricular (RV) function in patients with acute respiratory syndrome (ARDS) is warranted because RV failure is frequent and associated with worse outcome. Transthoracic echocardiography is the cornerstone of RV assessment but it remains challenging. Quantification of RV deformation by speckle-tracking imaging echocardiography (STE) is a widely available and reproducible technique that readily provides an integrated analysis of all segments of the RV. This study aims to investigate the accuracy of STE-derived strain parameters in assessing RV function during ARDS.
Interventions
None listed
Sponsors
Central Hospital, Nancy, France
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients with moderate or severe ARDS (Berlin definition) * receiving mechanical ventilation (\>48h estimated length) * Transthoracic echocardiography performed during the first 36h after ICU admission
Exclusion criteria
* pregnancy * protected or deprived of Liberty major * chronic respiratory disease * history of clinical right heart failure * chronic heart failure with LVEF \< 35% * severe valvular heart disease * under 18 or protected-adults
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measure of longitudinal peak systolic strain | up to 36 hours after Intensive Care Unit admission |
Secondary
| Measure | Time frame |
|---|---|
| Measure of PaO2/FiO2 ratio | up to 36 hours after Intensive Care Unit admission |
| Ventilator-free days | 28 days |
| Mortality | 28 days |
Countries
France
Outcome results
None listed