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Stress Level and the Relationship With IVF Outcomes.

Does Stress Affect In-Vitro Fertilization (IVF) Outcome?

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02638662
Enrollment
276
Registered
2015-12-23
Start date
2010-07-31
Completion date
2020-02-29
Last updated
2020-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Brief summary

The effect of stress on IVF outcomes.

Detailed description

The purpose of this study is to describe the pattern of psychological distress (depression, anxiety and stress) as assessed by both subjective and objective measures throughout the course of IVF treatment and to investigate its impact on IVF outcome.

Interventions

OTHERObservational

Questionnaires are completed such as self-evaluation questionnaire (STAI), Beck Depression Inventory, FertiQol International and Daily stress questionnaire

Sponsors

Weill Medical College of Cornell University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
20 Years to 44 Years
Healthy volunteers
No

Inclusion criteria

* Healthy women undergoing IVF at CRMI Ages 20-44 Patients will be divided in different groups depending on whether: 1. They are donating oocytes (control group). 2. They are undergoing IVF for the first time. 3. They are undergoing IVF for the third time and have either failed or succeeded the prior time.

Exclusion criteria

* Any patients who are not candidates for IVF * Any women who have any past or current medical condition unrelated to their infertility concurrent to their history of infertility (e.g., gastrointestinal disease)

Design outcomes

Primary

MeasureTime frame
Biomarkers Cortisol and adrenocorticotropic hormone ACTH.28-35 days

Secondary

MeasureTime frameDescription
Questionnaires to be completed are Life Orientation Test-R28-35 days
Self- Evaluation Questionnaire (STAI)28-35 daysQuestionnaire
FertiQOL International28-35 days
Beck Depression Inventory28-35 daysQuestionnaire
Daily Stress Questionnaire28-35 daysQuestionnaire

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026