Application of Ultrasonic Elastography in Lung Lesions

Transthoracic Ultrasound Elastography in Pulmonary Lesions and Diseases

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02636985

Enrollment

Registered

2015-12-22

Start date

2011-12-31

Completion date

2013-03-31

Last updated

2015-12-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elastography

Brief summary

Elastography is an imaging of tissue elasticity or stiffness and is currently emerging as a mainstream tool for ultrasound-based diagnosis. This compressibility property of materials, mathematically expressed as the change in tissue displacement as a function of its distance from the compressing device, is known as strain and is the parameter that is imaged in an elastogram. Elastography has currently shown promising result in differentiating viscoelastic nature of various organs, which is a consequence of certain underlying diseases. At present, there are limited literatures revealing the application and feasibility of ultrasonic elastography in lung lesions. This is essentially important as it may serve as an adjuvant to B-mode ultrasound. The investigators aimed at exploring the application and feasibility of ultrasonic elastography on lung lesions.

Detailed description

Patients performed conventional B-mode ultrasound, subsequently followed by ultrasound elastography. The strain ration was measured and was compared between necrosis, atelectasis, consolidation and tumor.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

A. Inclusion Criteria: Patients with radiographic findings of: 1. consolidation 2. obstructive pneumonitis 3. tumors B.

Exclusion criteria

1. Patients with poor acoustic window 2. Unable to hold breathing 3. Not cooperative 4. Presence of pleural effusion

Design outcomes

Primary

Measure	Time frame	Description
Comparison of strain ratio between necrosis, atelectasis, consolidation and tumor	Up to 15 months	The strain ratio was measured under ultrasonic elastography. At least three measurements were performed each time and we average all the measurements as the final strain ratio. Independent t test was used for comparison.

Countries

Taiwan

Outcome results