Immediate Intra Uterine Isemination (IUI) Versus Expectant Management in Postoperative Endometriosis Patients

Is Postoperative IUI Better Than Expectant Management in Infertile Endometriosis Patients With Good Prognosis Based on EFI Score?

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02636400

Enrollment

Registered

2015-12-21

Start date

2014-02-28

Completion date

2018-01-26

Last updated

2024-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis, Infertility

Keywords

Infertility, endometriosis

Brief summary

Is postoperative IUI better than expectant management in infertile endometriosis patients with good prognosis based on their EFI score? (A single centre randomised controlled trial).

Interventions

OTHERcontrolled ovarian stimulation with gonadotropins + intrauterine insemination

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 37 Years

Healthy volunteers

Inclusion criteria

* recent (\<6months) complete laparoscopic endometriosis resection * endometriosis fertility index (EFI) at least 7/10 * Regular menstrual cycles (min 24days - max 38days) with proven ovulation * At least one functional tube at surgery, normal uterus * Sperm sample of partner: normal or mild male factor

Exclusion criteria

* frozen (donor or partner) sperm * clinical and/or imaging evidence of endometriosis recurrence/persistence at randomization * FSH \> 20 IU/L

Design outcomes

Primary

Measure	Time frame
cumulative clinical pregnancy rate	participants will be followed for the duration of 7 menstrual cycles and in case of pregnancy, they will be followed until the pregnancy outcome is known, implying an average time frame of 1.5 year

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026