Peripheral Nerve Blocks in Elderly Patients With Hip Fracture

A Randomized Controlled Trial of Comparing Two Methods of Nerve Block in Combination With Laryngeal Mask Anesthesia Effect for Hip Fracture on Post-operative Quality of Recovery in Elderly Patients

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02635763

Enrollment

Registered

2015-12-21

Start date

2015-10-31

Completion date

2016-06-30

Last updated

2015-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip Fracture

Keywords

nerve block, general anesthesia, hip fracture, recovery

Brief summary

As the population ages, the frequency of surgery is increasing proportionally, bringing with it the challenge of managing older patients with frequent comorbid diseases and an increased risk of complications. Poor postoperative quality of recovery may result in patient and family suffering, a prolonged hospital stay, and a greater demand on health care resources.The purpose of this study was to evaluate the ultrasound guided percutaneous femoral nerve+lateral cutaneous nerve versus lumbar plexus+sacral plexus nerve block composite laryngeal mask anesthesia in elderly hip fracture surgery, the application of assessing their impact on the postoperative recovery quality.

Detailed description

In this study, patients who were more than 65 years old with hip fracture were randomized to peripheral nerve blocks 1(PNBs1)- femoral nerve+lateral cutaneous nerve-with laryngeal mask anesthesia, or peripheral nerve blocks 2(PNBs2) - lumbar plexus and sciatic - with laryngeal mask anesthesia. Blocks were performed using ultrasound and 0.5% ropivacaine. All patients received postoperative multimodal analgesia. Postoperative recovery was assessed at 15 minutes, 40 minutes,- 1 day, 3 days, and 7 days after surgery, with the Postoperative Quality of Recovery Scale, in physiological, nociceptive, emotive, modified activities of daily living, modified cognitive, and overall patient perspective domains.

Interventions

PROCEDUREFemoral nerve and the lateral cutaneous nerve block

Femoral nerve block was performed using 0.5% ropivacaine (15ml) under ultrasound guide;the lateral cutaneous nerve block was performed using 0.5% ropivacaine (5ml) under ultrasound guide

PROCEDURELumbar plexus and sacral plexus nerve block

Lumbar plexus block was performed using 0.5% ropivacaine (25ml) under ultrasound guide; sacral plexus nerve block was performed using 0.5% ropivacaine (15ml) under ultrasound guide

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

65 Years to 85 Years

Healthy volunteers

Inclusion criteria

1. ASA grade I \ III level; 2. The BMI \<30; 3. The Mini - getting the state examination MMSE \> 23; 4. The operation type:open reduction and internal fixation or bipolar head replace.

Exclusion criteria

1. Serious systemic diseases such as respiratory dysfunction, cardiac insufficiency, and renal insufficiency; 2. Has a history of cognitive function disorder or mental illness; 3. Has a history of cerebral infarction and leave sequela; 4. The blood coagulation dysfunction; 5. The hearing or visual impairment; 6. Unable to complete assessment; 7. Operation time more than 90 minutes; 8. The bleeding is greater than 1000 ml.

Design outcomes

Primary

Measure	Time frame
postoperative quality of recovery	3 days after operative

Countries

China

Contacts

Primary ContactQingfu Zhang, master

zhangqingfu1228@163.com86-18930173672

Backup ContactJunfeng Zhang, PhD

zhangjunfeng@sjtu.edu.cn86-18930173672

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026