Gynecological Disorders
Conditions
Keywords
Si Wu Tang, antioxidation, anthropometric measurements, liver, skin
Brief summary
The purpose of the current study was to check the physiological improvement of SWT on liver and skin and also the antioxidation in healthy adults.
Detailed description
Background: Si-Wu-Tang (SWT) is a well-known traditional Chinese medicine (TCM) and widely used for treating various gynecological disorders. The purpose of the current study was to check the physiological improvement of SWT on liver and skin and also the antioxidation in healthy adults. Methods: Sixty healthy voluntary subjects were recruited and assigned into two groups, who drank 125 mL of placebo (n=30) or SWT (n=30) for 6 continuous days per month during the following 6 months and vice versa with one month of washout period in between. During the initial, 3rd, 6th, 10th, and 13th months anthropometric measurements were performed as well as fasting blood samples were drawn for various biochemical assays. Abdominal ultrasonic and skin examination were performed at the initial, 6th and 13th months.
Interventions
OTHERSi-Wu-Tang (SWT)
The purpose of the current study was to check the physiological improvement of SWT on liver and skin and also the antioxidation in healthy adults.
OTHERplacebo
The purpose of the current study was to check the physiological improvement of placebo on liver and skin and also the antioxidation in healthy adults.
Sponsors
Chung Shan Medical University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy adults
Exclusion criteria
*
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total thiobarbituric acid reactive substances (TBARS) | 6 months |
Secondary
| Measure | Time frame |
|---|---|
| Total antioxidant capacity (TEAC)activities. | 6 months |
| Superoxide dismutase (SOD) activity | 6 months |
| GPx and glutathione reductase (GR) activity | 6 months |
| Catalase | 6 months |
| Glutamic oxaloacetic transaminase (GOT) | 6 months |
| Glutamic pyruvic transaminase (GPT) | 6 months |
| Glutathione content (GSH) | 6 months |
Other
| Measure | Time frame |
|---|---|
| Skin surface water loss | 6 months |
| Skin melanin index | 6 months |
| Skin elasticity | 6 months |
| Skin hydration | 6 months |
| Skin sebum content | 6 months |
Outcome results
None listed